Improved rheumatoid digital vasculitis in a patient treated with TNFα agent blocking (infliximab)
Identifieur interne : 001993 ( Main/Exploration ); précédent : 001992; suivant : 001994Improved rheumatoid digital vasculitis in a patient treated with TNFα agent blocking (infliximab)
Auteurs : Maurizio Benucci [Italie] ; Francesca Li Gobbi [Italie] ; Gianantonio Saviola [Italie] ; Mariangela Manfredi [Italie]Source :
- Rheumatology International [ 0172-8172 ] ; 2008-10-01.
English descriptors
Abstract
Abstract: Rheumatoid vasculitis (RV) is an uncommon but potentially catastrophic complication of rheumatoid arthritis (RA). There are few current extensive studies and no consensus regarding the clinical, laboratory, histologic features and management or prognosis of RV. We report a case of RV in a 74-year old woman with a long (14 years) history of RA, who developed vasculitis of distal arteries with gangrene of digits of upper and lower extremities. After the failure of various immunosuppressive drugs (cyclophosphamide, methotrexate), the patient was treated with anti-TNFalpha infliximab. Digital gangrene healed within four months from the start of anti-TNFalpha treatment.
Url:
DOI: 10.1007/s00296-008-0592-x
Affiliations:
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